Research Fellow in the Laboratory of Assistant Professor Dinesh Kumar Srinivasan
Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University, Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. Lee Kong Chian School of Medicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and Nanyang Technological University. The first cohort of 50 students will start in August 2013.
Cardiac malformations are frequently observed in infants of diabetic mothers. Hyperglycemia causes the cellular oxidative damage by increasing production of reactive oxygen species (ROS). The increased level of ROS causes the free radical generation and decreased antioxidants or both, which eventually influence the organogenesis during development. It is anticipated that intervention of the regulatory network may reveal new therapeutic rationale and drug targets. This project will use mouse models of diabetic embryopathy.
Our goals include:
1) to explore the pathogenesis of diabetic embryopathy
2) to develop novel, more refined therapeutic strategies to combat this devastating condition
3) to speed up translation of basic research into clinical practice
Successful candidates will have a track record of research excellence as a postdoctoral worker in a related or relevant field. Requirements include PhD in Molecular Biology/ Life Sciences or related fields, knowledge and experience in animals, cell culture, immunohistochemistry and molecular biology and experience in writing grant proposals would be advantageous.
Application Procedure:
If you are interested to pursue a career with the School, please apply to Ms Esabelle Yam, Assistant Manager, Research Programmes (email: esabelleyam@ntu.edu.sg) with your CV,list of publications, statement of research interests and names of three references at your earliest convenience.
Only shortlisted candidates will be notified.
Closing date: 31 July 2013
Laboratory Executive
Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University, Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. Lee Kong Chian School of Medicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and Nanyang Technological University. The first cohort of 50 students will start in August 2013.
The Laboratory Executive’s duties include, but not limited to:
- Manage day-to-day laboratory activities
- Manage research accounts of Principal Investigators (PIs);
- Manage waste (chemical, biohazard, radioactive) disposal;
- Manage and update equipment and chemicals inventories;
- Manage equipment contract services and contact suppliers to troubleshoot any potential problems;
- Maintain laboratory safety in accordance to institutional requirements;
- Advice and guide laboratory staff to solve technical problems;
- Develop and implement laboratory Standard Operational Procedure (SOPs) and Risk assessments (RAs);
- Assure that laboratory staff is trained and follows standard operating procedures (SOPs) and equipment technical requirements;
- Research procurement i.e. order material and laboratory supplies and
- Liaison between administrative staff, research investigators and collaborating laboratories and/or facilities.
Skills and qualifications:
Successful candidates will have a Diploma Degree in Biomedical Sciences or related discipline; a Bachelor’s Degree will be advantageous. A minimum of 3 years research laboratory experience which includes interacting with staff and laboratory day-to-day activities is required. The candidate should have experience in institutional research protocol work-flow such as IACUC and IRB application, chemical and biological safety and preferably also animal handling. Qualities that he/she should possess are self-motivation to work in a fast-paced research environment, ability to multi-task, good command of English and good interpersonal and communication skills.
Application Procedure:
If you are interested to pursue a career with the School, please apply to Ms Esabelle Yam, Assistant Manager, Research Programmes (email: esabelleyam@ntu.edu.sg) with your CV and names of three references at your earliest convenience.
Only shortlisted candidates will be notified.
Closing date: 20th June 2013
Research Fellows in the Laboratory of Professor Walter Wahli
Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University, Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. Lee Kong Chian School of Medicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and Nanyang Technological University. The first cohort of 50 students will start in August 2013.
LKCMedicine is currently recruiting three Research Fellows who will be working closely with Professor Walter Wahli, Visiting Professor at LKCMedicine in the development of competitive independent research and contribute to the teaching of medical students. This post will assist in conducting research work in the Laboratory of Professor Wahli on his research in Metabolic Diseases. The research will focus on questions which will be part of a broader Singaporean programme, concentrating on late pregnancy and early postnatal life, with aims to identify molecular mechanisms and molecules, emanating from the interplay between nutrients and microbiota in relation to obesity and associated metabolic diseases.
Within the field of Metabolic Diseases, this post will be required to conduct research in relation to metabolism, molecular biology and genomics. S/he would be involved in projects which use mouse models to investigate:
- Energy metabolism in health and disease during late gestation and early life;
- Diet (fat/carbohydrate rich; micronutrient deficient) -induced tissue damages and associated inflammatory and repair responses; and
- Host - microbiome interactions in metabolic deregulations/diseases
- The appointees will have the opportunity to work in a dynamic environment with experienced molecular and cell biologists, geneticists, and microbiologists. They will have access to leading edge core facilities
- Successful candidates will have a MD-PhD or a PhD qualification in molecular physiology, biochemistry, cell/molecular biology, with experience in protein and nucleic acid biochemistry, and mouse genetics. Previous publications in international peer reviewed journals are a prerequisite.
Application Procedure:
If you are interested to pursue a career with the School, please apply to Ms Esabelle Yam, Assistant Manager, Research Programmes (email: esabelleyam@ntu.edu.sg) with your CV, list of publications, statement of research interests and names of three references at your earliest convenience.
Only shortlisted candidates will be notified.
Closing date: 13 March 2013
Research Appointment
The School is developing an innovative five-year undergraduate course in Medicine that will produce the doctors of tomorrow for Singapore. The research strategy of the School builds on existing competencies at Nanyang Technological University and clinical opportunities at our healthcare partners, as well as areas of mutual interest between Imperial College London and Nanyang Technological University, with the aim to bridge research in medicine and engineering.
Cardiac malformations are frequently observed in infants of diabetic mothers. Hyperglycemia causes the cellular oxidative damage by increasing production of reactive oxygen species (ROS). The increased level of ROS causes the free radical generation and decreased antioxidants or both, which eventually influence the organogenesis during development. It is anticipated that intervention of the regulatory network may reveal new therapeutic rationale and drug targets. This project will use mouse models of diabetic embryopathy. Our goals include: 1) to explore the pathogenesis of diabetic embryopathy; 2) to develop novel, more refined therapeutic strategies to combat this devastating condition; and 3) to speed up translation of basic research into clinical practice.
Key Responsibilities
Job Purpose:
The appointee is expected to carry out high quality research and would include the following activities:
1. Publishing in high impact factor journals
2. Attending and presenting research findings at international meetings
3. Any other tasks as assigned by principal investigator
The appointee may be involved in supervising and teaching of medical students on modules relating to cardiovascular biology and diabetes.
Person Specification
Criteria
Qualifications, Knowledge and Experience:
- PhD in Molecular Biology/ Life Sciences or related fields
- Knowledge and experience in animals, cell culture, immunohistochemistry and molecular biology
- Experience in writing grant proposals would be advantageous
Management and Teamwork:
- Ability to work as part of a multidisciplinary team
- Ability to work co-operatively with medical and non-medical staff
Communicating and Influencing:
- Ability to communicate effectively with staff
- Ability to motivate others
- Presentation skills
- Ability to work in a team
Special Requirements:
- Willing to participate in educating and training of medical students
Time Commitment
- This is a full time position
Research Fellow in the Laboratory of Professor Michael A. Ferenczi
Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University (NTU), Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. LKCMedicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and NTU. The first cohort of 50 students will start in August 2013.
Lee Kong Chian School of Medicine (LKCMedicine) is a new joint medical school by Imperial College London and Nanyang Technological University (NTU), Singapore. It was established in September 2010 and will operate from two campuses – Yunnan Campus at Nanyang Technological University and a new campus to be built at Novena. Its primary healthcare partner is the National Healthcare Group (NHG) which comprises an integrated network of primary healthcare polyclinics, acute care hospitals such as Tan Tock Seng Hospital, and national specialty centres. LKCMedicine will deliver a new five-year undergraduate medical programme resulting in a joint degree (MBBS) awarded by Imperial College London and NTU. The first cohort of 50 students will start in August 2013.
The Muscle Biophysics Laboratory of Professor Michael A. Ferenczi is a new laboratory following the move of Professor Ferenczi from Imperial College London to Singapore, where Professor Ferenczi has joined the new medical school at NTU as Assistant Dean and Head of Phase 1. A new scientific environment is being created, taking advantage of the well-established research excellence of the College of Sciences in engineering and biological sciences disciplines. NTU is a rapidly rising star in the research landscape which provides excellent facilities and opportunities. Singapore is a tropical experience, which combines modern living with the exoticism of Asia. LKCMedicine is currently recruiting a Research Fellow in Metabolic Diseases who will be working closely with Professor Ferenczi in the development of competitive independent research and contribute to the teaching of medical students. This post will assist in conducting research work in the Muscle Biophysics Laboratory of Professor Ferenczi, with the aim to understand the role of phosphorylation in the modulation of cardiac contraction in health and disease. In his research, Professor Ferenczi explores how the heart modulates its output and performance by changing the phosphorylation level of important protein components. This is to understand the type of changes which are beneficial to cardiac function and those which are linked to phases in cardiac disease progression, with a view to explore ways to minimize or slow down deterioration in cardiac performance.
Successful candidates will have a track record of research excellence as a postdoctoral worker in a related or relevant field. Applicants with engineering, physics or biology background would be welcome. Ability to deal with optics, microscopy, electronics and Labview programming would be advantageous. Expertise in molecular biology, cell biology and physiology would also be an added advantage.
Application Procedure:
If you are interested to pursue a career with the School, please apply to Ms Lydia Tan, Director, Human Resources (email: hr_LKCMedicine@ntu.edu.sg) with your CV, list of publications, statement of research interests and names of three references at your earliest convenience. For further queries, you may write to Professor Michael A. Ferenczi, Professor, Assistant Dean and Head of Phase 1 of LKCMedicine (email: m.ferenczi@ntu.edu.sg).
Only shortlisted candidates will be notified.
Closing date: 31 December 2012