2014 Publications



  • Kundu P, Ling TW, Korecka A, Li Y, D'Arienzo R, Bunte RM, Berger T, Arulampalam V, Chambon P, Mak TW,  Wahli W, Pettersson S. Absence of Intestinal PPARγ Aggravates Acute Infectious Colitis in Mice through a Lipocalin-2–Dependent Pathway. 2014. PLoS Pathog. [Pubmed]

  • Luo D. Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors. 2014. RNA Biol. [Pubmed]

  • Loo LS, Tang N, Al-Haddawi M, Dawe G, Hong W. A role for Sorting Nexin 27 in AMPA Receptor trafficking. 2014. Nat Comm. [Pubmed]



  • Min Y, Li J, Liu F, Padmanabhan P, Yeow EKL, Xing B. Recent Advance of Biological Molecular Imaging Based on Lanthanide-Doped Upconversion-Luminescent Nanomaterials. 2014. Nanomaterials.

  • Wilder-Smith A, Quam M, Sessions O, Rocklov J, Liu-Helmersson J, Franco L, Khan K. The 2012 dengue outbreak in Madeira: exploring the origins. 2014. Euro Surveill. [Pubmed]

  • Tan NS, Wahli W. The emerging role of Nrf2 in dermatotoxicology.  2014. EMBO Mol Med. [Pubmed]

  •  Heiney SA, Kim J, Augustine GJ, Medina JF. Precise control of movement kinematics by optogenetic inhibition of Purkinje cell activity. 2014.  J Neurosci. [Pubmed]



  • van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S. Divergence of zebrafish and mouse lymphatic cell fate specification pathways. 2014. Development. [Pubmed]

  • Rolfe A, Cash-Gibson L, Car J, Sheikh A, McKinstry B. Interventions for improving patients' trust in doctors and groups of doctors. 2014. Cochrane Database Syst Rev. [Pubmed]

  • Liu-Helmersson J, Stenlund H, Wilder-Smith A, Rocklöv J. Vectorial Capacity of Aedes aegypti: Effects of Temperature and Implications for Global Dengue Epidemic Potential. 2014. PLoS One. [Pubmed]

  • Song W and Wang X. The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure. 2014. Biophysical Reviews



  • Tan NS, Wahli W. The emerging role of Nrf2 in dermatotoxicology. 2014. EMBO Mol Med.  [Pubmed]

  • Singh S, Papareddy P, Mörgelin M, Schmidtchen A, Malmsten M. Effects of PEGylation on membrane and lipopolysaccharide interactions of host defense peptides. 2014. Biomacromolecules. [Pubmed]



  • Papareddy P, Kalle M, Singh S, Mörgelin M, Schmidtchen A, Malmsten M. An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo. 2014. Biochim Biophys Acta. [Pubmed]
  • Wilder-Smith A, Macary P. Dengue: Challenges for Policy Makers and Vaccine Developers. 2014. Curr Infect Dis Rep. [Pubmed]
  • YQuam M, Massad E, Wilder-Smith A. Effects of India's new polio policy on travellers. 2014. Lancet.



  • Palomer X, Capdevila-Busquets E, Botteri G,  Salvadó L, Barroso E, Davidson M M, Michalik L,Wahli W, Vázquez-Carrera M. PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells. 2014.  Int J Cardiol. [Pubmed]
  • Lim PL. Travel and the globalization of emerging infections. 2014. Trans R Soc Trop Med Hyg. [Pubmed]
  • Rasmussen K, Belisario JM, Wark PA, Molina JA, Loong SL, Cotic Z, Papachristou N, Riboli-Sasco E, Tudor Car L, Musulanov EM, Kunz H, Zhang Y, George PP, Heng BH, Wheeler EL, Al Shorbaji N, Svab I, Atun R, Majeed A, Car J.  Offline eLearning for undergraduates in health professions: A systematic review of the impact on knowledge, skills, attitudes and satisfaction. 2014.  J Glob Health. [Pubmed]
  • Khan K, Bogoch I, Brownstein JS, Miniota J, Nicolucci A, Hu W, Nsoesie EO, Cetron M, Creatore MI, German M, Wilder-Smith A. Assessing the Origin of and Potential for International Spread of Chikungunya Virus from the Caribbean. 2014. PLOS Currents Outbreaks. [Pubmed]
  • Chotirmall SH, Mirkovic B, Lavelle GM, McElvaney NG. Immunoevasive Aspergillus Virulence Factors. 2014. Mycopathologia. [Pubmed]
  • Massad E, Wilder-Smith A, Ximenes R, Amaku M, Lopez LF, Coutinho FA, Coelho GE, Silva JB Jr, Struchiner CJ, Burattini MN. Risk of symptomatic dengue for foreign visitors to the 2014 FIFA World Cup in Brazil. 2014. Mem Inst Oswaldo Cruz. [Pubmed]
  • George PP, Papachristou N, Belisario JM, Wang W, Wark PA, Cotic Z, Rasmussen K, Sluiter R, Riboli-Sasco E, Tudor Car L, Musulanov EM, Molina JA, Heng BH, Zhang Y, Wheeler EL, Al Shorbaji N, Majeed A, Car J. Online eLearning for undergraduates in health professions: A systematic review of the impact on knowledge, skills, attitudes and satisfaction. 2014. J Glob Health. [Pubmed]
  • Rocklöv J, Lohr W, Hjertqvist M, Wilder-Smith A. Attack rates of dengue fever in Swedish travellers. 2014. Scand J Infect Dis.
  • Scharnagl H, Kleber ME, Genser B, Kickmaier S, Renner W, Weihrauch G, Grammer T, Rossmann C, Winkelmann BR, Boehm BO, Sattler W, März W, Malle E. Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography--the LURIC study. 2014. Int J Cardiol.
  • Thein TL, Lye DC, Leo YS, Wong JG, Hao Y, Wilder-Smith A. Severe neutropenia in dengue patients: prevalence and significance. 2014. Am J Trop Med Hyg.



  • Ong ST, Freeley M, Skubis-Zegadło J, Fazil MH, Kelleher D, Fresser F, Baier G, Verma NK, Long A. Phosphorylation of Rab5a by protein kinase Cε is crucial for T-cell migration. 2014. J Biol Chem. [Pubmed]
  • Wu H, Ng BS, Thibault G. Endoplasmic Reticulum Stress Response in Yeast and Humans. 2014. Bioscience Reports Immediate Publication. [Pubmed]
  • Massad E, Burattini MN, Ximenes R, Amaku M, Wilder-Smith A. Dengue outlook for the World Cup in Brazil. 2014. Lancet Infect Dis. [Pubmed]
  • Fløyel T, Brorsson C, Nielsen LB, Miani M, Bang-Berthelsen CH, Friedrichsen M, Overgaard AJ, Berchtold LA, Wiberg A, Poulsen P, Hansen L, Rosinger S, Boehm BO, Ram R, Nguyen Q, Mehta M, Morahan G, Concannon P, Bergholdt R, Nielsen JH, Reinheckel T, von Herrath M, Vaag A, Eizirik DL, Mortensen HB, Størling J, Pociot F. CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients. 2014. Proc Natl Acad Sci U S A. [Pubmed]
  • Kalle M, Papareddy P, Kasetty G, van der Plas MJA, Mörgelin M, Malmsten M, Schmidtchen A. A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection. 2014.  PLoS ONE. [Pubmed]
  • Wilder-Smith A. Dengue vaccines: dawning at last?. 2014. Lancet. [Pubmed]
  • Li L, Trifunovic A, Köhler M, Wang Y, Berglund JP, Illies C, Juntti-Berggren L, Larsson NG, Berggren PO. Defects in β-Cell Ca2+ Dynamics in Age-Induced Diabetes. 2014. Diabetes. [Pubmed]



  • Kundu P, Pettersson S. Immunology: Mammalian watchdog targets bacteria. 2014. Nature. [Pubmed]

  • Zhou YP, Wilder-Smith A, Hsu LY. The Role of International Travel in the Spread of Methicillin-Resistant Staphylococcus aureus. 2014. J Travel Med. [Pubmed]

  • Banks SD, Murray N, Wilder-Smith A, Logan JG. Insecticide-treated clothes for the control of vector-borne diseases: A review on effectiveness and safety. 2014. Med Vet Entomol. [Pubmed]

  • Singh S, Papareddy P, Kalle M, Schmidtchen A, Malmstena M. Effects of linear amphiphilicity on membrane interactions of C-terminal thrombin peptides. 2014. RSC Adv.

  • Chmiel JF, Aksamit TR, Chotirmall SH, Dasenbrook EC, Elborn JS, LiPuma JJ, Ranganathan SC, Waters VJ, Ratjen FA. Antibiotic Management of Lung Infections in Cystic Fibrosis: Part II. Nontuberculous Mycobacteria, Anaerobic Bacteria, and Fungi. 2014. Ann Am Thorac Soc. [Pubmed]

  • Nikolaev SI, Garieri M, Santoni F, Falconnet E, Ribaux P, Guipponi M, Murray A, Groet J, Giarin E, Basso G, Nizetic D, Antonarakis SE. Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations. 2014. Nature Communications.



  • Zhang Y, Das GK, Vijayaragavan V, Xu QC, Padmanabhan P, Bhakoo KK, Tamil Selvan S, Tan TT. "Smart" theranostic lanthanide nanoprobes with simultaneous up-conversion fluorescence and tunable T1-T2 magnetic resonance imaging contrast and near-infrared activated photodynamic therapy. 2014. Nanoscale. [Pubmed]
  • Chmiel JF, Aksamit TR, Chotirmall SH, Dasenbrook EC, Elborn JS, LiPuma JJ, Ranganathan SC, Waters VJ, Ratjen FA. Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-Resistant Staphylococcus aureus, Gram-Negative Bacteria, and Multiple Infections. 2014. Ann Am Thorac Soc. [Pubmed]
  • Merza M, Rahman M, Zhang S, Hwaiz R, Regnér SM, Schmidtchen A, Thorlacius H. Human thrombin-derived host defense peptides inhibit neutrophil recruitment and tissue injury in severe acute pancreatitis. 2014. Am J Physiol Gastrointest Liver Physiol. [Pubmed]
  • Papareddy P, Kalle M, Bhongir RK, Mörgelin M, Malmsten M, Schmidtchen A. Antimicrobial effects of helix D-derived peptides of human antithrombin III. 2014.  J Biol Chem. [Pubmed]
  • Zimdahl H, Ittrich C, Graefe-Mody U, Boehm BO, Mark M, Woerle HJ, Dugi KA. Influence of TCF7L2 gene variants on the therapeutic response to the dipeptidylpeptidase-4 inhibitor linagliptin. 2014. Diabetologia. [Pubmed]
  • Peh MT, Anwar AB, Ng DS, Atan MS, Srinivasan DK, Moore PK. Effect of feeding a high fat diet on hydrogen sulfide (H2S) metabolism in the mouse. 2014. Nitric Oxide. [Pubmed]
  • Tozan Y, Ratanawong P, Louis VR, Kittayapong P, Wilder-Smith A. Use of Insecticide-Treated School Uniforms for Prevention of Dengue in Schoolchildren: A Cost-Effectiveness Analysis. 2014. PLoS One. [Pubmed]
  • Murray N, Jansarikij S, Olanratmanee P, Maskhao P, Souares A, Wilder-Smith A, Kittayapong P, Louis VR. Acceptability of impregnated school uniforms for dengue control in Thailand: a mixed methods approach. 2014. Glob Health Action. [Pubmed]
  •  Gandhimathi C, Venugopal JR, Bhaarathy V, Ramakrishna S, Srinivasan DK. Biocomposite nanofibrous strategies for the controlled release of biomolecules for skin tissue regeneration. 2014. Int J Nanomedicine.



  • Holmkvist P, Roepstorff K, Uronen-Hansson H, Sandén C, Gudjonsson S, Patschan O, Grip O, Marsal J, Schmidtchen A, Hornum L, Erjefält JS, Håkansson K, Agace WW. A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality. 2014. Mucosal Immunol. [Pubmed]
  • Pérez-Schindler J, Svensson K, Vargas-Fernández E, Santos G, Wahli W, Handschin C. The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet. 2014. Diabetologia. [Pubmed]
  • Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E,Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, el (…Boehm BO…). Defining the role of common variation in the genomic and biological architecture of adult human height. 2014. Nature Genetics. 2014. [Pubmed]
  • Schneider JG, Isermann B, Kleber ME, Wang H, Boehm BO, Grammer TB, Prueller F, Nawroth PP, Maerz W. Inverse association of the endogenous thrombin potential (ETP) with cardiovascular death: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. 2014. International Journal of Cardiology. [Pubmed]
  • Rawling DC, Kohlway AS, Luo D, Ding SC, Pyle AM. The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain. 2014. Nucleic Acids Research. [Pubmed]
  • Kohlway A, Pirakitikulr N, Ding SC, Yang F, Luo D, Lindenbach BD, Pyle AM. The linker region of NS3 plays a critical role in the replication and infectivity of hepatitis C virus. 2014. Journal of Virology. [Pubmed]
  • Al-Alawi M, Hassan T, Chotirmall SH. Transforming growth factor b and severe asthma: A perfect storm. 2014. Respiratory Medicine. [Pubmed]
  • Paul Murima, John D. McKinney, Kevin Pethe. Targeting Bacterial Central Metabolism for Drug Development. 2014. Chemistry & Biology.
  • Almaça J, Molina J, Drigo RA, Abdulreda MH, Won BJ, Berggren PO, Caicedo A, Hong GN. Young Capillary Vessels Rejuvenate Aged Pancreatic Islets. 2014. Proceedings of the National Academy of Sciences.
  • Salvadó L, Barroso E, Gómez-Foix AM, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M. PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. 2014. Diabetologia. [Pubmed]
  • Braniste V, Al-Asmakh M, Kowal C, Anuar F, Abbaspour A, Tóth M, Korecka A, Bakocevic N, Ng LG,  Kundu P,  Gulyás B, Halldin C, Hultenby K, Nilsson H, Hebert H, Volpe BT, Diamond B, Pettersson S. The Gut Microbiota Influences Blood-Brain Barrier Permeability In Mice. 2014. Science Translational Medicine.
  • Verma NK, Kelleher D. Adaptor regulation of LFA-1 signaling in T lymphocyte migration: Potential druggable targets for immunotherapies? 2014. European Journal of Immunology.
  • Nikolaev SI, Garieri M, Santoni F, Falconnet E, Ribaux P, Guipponi M, Murray A, Groet J, Giarin E, Basso G, Nizetic D, Antonarakis SE. Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations. 2014. Nature Communications.
  • Tóth M, Häggkvist J, Varrone A, Finnema SJ, Doorduin J, Tokunaga M, Higuchi M, Gulyás B, Halldin C. ABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [ (11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pig. 2014. EJNMMI Research.



  • Zheng J, Yong HY, Panutdaporn N, Liu CF, Tang K, Luo DH. High resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5. 2014. Nucleic Acids Research.
  • Jade KP, Verma NK, Niamh MO, Miriam C, Mary JM, and Daniela MZ. Combretastatin (CA)-4 and its novel analogue CA-432 impair T-cell migration through the Rho/ROCK signalling pathway. 2014. Biochemical Pharmacology.