2016 Publications

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January

Lopez LF, Amaku M, Coutinho FA, Quam M, Burattini MN, Struchiner CJ, Wilder-Smith A, Massad E. Modeling Importations and Exportations of Infectious Diseases via Travelers. 2016. Bull Maths Biol.

Lim JK, Lee YS, Wilder-Smith A, Thiry G, Mahoney R, Yoon IK. Points for Consideration for dengue vaccine introduction – recommendations by the Dengue Vaccine Initiative. 2016. Expert Rev Vaccines.

Wilder-Smith A, Massad E. Age specific differences in efficacy and safety for the CYD-tetravalent dengue vaccine. 2016. Expert Rev Vaccines.

Berglund K, Clissold K, Li HE, Wen L, Park SY, Gleixner J, Klein ME, Lu D, Barter JW, Rossi MA, Augustine GJ, Yin HH, Hochgeschwender U. Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation. 2016. PNAS

Chen S, Augustine GJ, Chadderton P. The cerebellum linearly encodes whisker position during voluntary movement. 2016. eLIFE.

Dalan R, Liew H, Assam PN, Chan ES, Siddiqui FJ, Tan AW, Chew DE, Boehm BO, Leow MK.A randomised controlled trial evaluating the impact of targeted vitamin D supplementation on endothelial function in type 2 diabetes mellitus: The DIMENSION trial. 2016.

Gernez Y, Walters J, Mirković B, Lavelle GM, Colleen DE, Davies ZA, Everson C, Tirouvanziam R, Silver E, Wallenstein S, Chotirmall SH, McElvaney NG, Herzenberg LA, Moss RB. Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis. 2016. Eur Respir J.

Greenfield G, Ignatowicz A, Gnani S, Bucktowonsing M, Ladbrooke T, Millington H, Car J, Majeed A. Staff perceptions on patient motives for attending GP-led urgent care centres in London: a qualitative study. 2016. BMJ Open

Muthu Selvam R, Vinothini G, Palliyarai Thaiyammal S, Latha S, Chinnathambi A, Dhanasekaran D, Padmanabhan P, Ali Alharbi S, Archunan G. The cell aggregating propensity of probiotic actinobacterial isolates: isolation and characterization of the aggregation inducing peptide pheromone. 2016. Biofouling

Piccenna L, Lannin NA, Scott K, Bragge P, Gruen RL. Guidance for community-based caregivers in assisting people with moderate to severe traumatic brain injury with transfers and manual handling: evidence and key stakeholder perspectives. 2016. Health Soc Care Community.

Ram R, Mehta M, Nguyen QT, Larma I, Boehm BO, Pociot F, Concannon P, Morahan G. Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility. 2016. J Immunol.

Dioa HJ, Wang K, Long HY, Wang M, Chew SY. Highly Fluorescent and Photostable Polymeric Nanofibers as Scaffolds for Cell Interfacing and Long-Term Tracking. 2015. Advance Healthcare Materials.


February

Montagner A, Polizzi A, Fouché E, Ducheix S, Lippi Y, Lasserre F, Barquissau V, Régnier M, Lukowicz C, Benhamed F, Iroz A, Bertrand-Michel J, Al Saati T, Cano P, Mselli-Lakhal L, Mithieux G, Rajas F, Lagarrigue S, Pineau T, Loiseau N, Postic C, Langin D, Wahli W, Guillou H. Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. 2016. Gut.

Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin A,Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals. 2016. Scientific Reports.

Tan CK and Wahli W. A trilogy of glucocorticoid receptor actions. 2016. PNAS.

Wilder-Smith A, Byass P. The elusive global burden of dengue. 2016. Lacent Infect Dis.

Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stünkel W. The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. 2016. Development.

Ali Y, Diez J, Selander L, Zheng X, Edlund H6, Berggren PO. The anterior chamber of the eye is a transplantation site that supports and enables visualisation of beta cell development in mice. 2016. Diabetologia.

Byass P, Wilder-Smith A. Utilising additional sources of information on microcephaly. 2016. The Lancet.

Maguire S, Chotirmall SH, Parihar V, Cormican L, Ryan C, O'Keane C, Redmond K, Smyth C. Isolated anterior mediastinal tuberculosis in an immunocompetent patient. 2016. BMC Pulm Med.

Piccenna L, Lannin NA, Gruen R, Pattuwage L, Bragge P. The experience of discharge for patients with an acquired brain injury from the inpatient to the community setting: A qualitative review. 2016. Brain Inj.

Thalagala N, Tissera H, Palihawadana P, Amarasinghe A, Ambagahawita A, Wilder-Smith A, Shepard DS, Tozan Y. Costs of Dengue Control Activities and Hospitalizations in the Public Health Sector during an Epidemic Year in Urban Sri Lanka. 2016. PLoS Negl Trop Dis

Wilder-Smith A, Yoon IK. Edging closer towards the goal of a dengue vaccine. 2016. Expert Rev Vaccines.

Velumani S, Toh YX, Balasingam S, Archuleta S, Leo YS, Gan VC, Thein TL, Wilder-Smith A, Fink K. Low antibody titers five years after vaccination with the CYD-TDV dengue vaccine in both pre-immune and naïve vaccinees. 2016. Hum Vaccin Immunother.

Ingham PW (2016). Segment polarity mutants and the rediscovery of the hedgehog pathway genes. Curr. Topics. Dev. Biol. 116:477-88.

Lee RT, Zhao Z, Ingham PW (2016). Hedgehog signalling. Development: 143(3): 367-72.

Tissera H, Amarasinghe A, Gunasena S, DeSilva AD, Yee LW, Sessions O, Muthukuda C, Palihawadana P, Lohr W, Byass P, Gubler DJ, Wilder-Smith A. Laboratory-Enhanced Dengue Sentinel Surveillance in Colombo District, Sri Lanka: 2012-2014. 2016. PLoS Negl Trop Dis. 

Ingham PW. Drosophila Segment Polarity Mutants and the Rediscovery of the Hedgehog Pathway Genes. 2016. Curr Top Dev Biol.

 

March

Grigg MJ, Barber BE, Marfurt J, Imwong M, William T, Bird E, Piera KA, Aziz A, Boonyuen U, Drakeley CJ, Cox J, White NJ, Cheng Q, Yeo TW, Auburn S, Anstey NM. Dihydrofolate-Reductase Mutations in Plasmodium knowlesi Appear Unrelated to Selective Drug Pressure from Putative Human-To-Human Transmission in Sabah, Malaysia. 2016.

Chung HL, Augustine GJ, Choi KW. Drosophila Schip1 Links Expanded and Tao-1 to Regulate Hippo Signaling. 2016. Developmental Cell

Vikhorev PG, Ferenczi MA, Marston SB. Instrumentation to study myofibril mechanics from static to artificial simulations of cardiac cycle. 2016. MethodsX.

Karmiloff-Smith A, Al-Janabi T, D'Souza H, Groet J, Massand E, Mok K, Startin C, Fisher E, Hardy J, Nizetic D, Tybulewicz V, Strydom A. The importance of understanding individual differences in Down syndrome. 2016. F1000Res.

 

April

Fox SJ, Fazil MHUT, Dhand C, Venkatesh M, Goh ETL, Harini S, Eugene C, Lim RR, Ramakrishna S, Chaurasia SS, Beuerman RW, Verma CS, Verma NK*, Loh XJ*, Lakshminarayanan R*. Insight into the membrane selectivity of linear and branched polyethylenimines and their potential as biocides for advanced wound dressings. 2016. Acta Biomater. *Corresponding authors.

Harini S, Venkatesh M, Radhakrishnan S, Fazil MHUT, Goh ETL, Rui S, Dhand C, Ong ST, Barathi AV, Beuerman RW, Ramakrishna S, Verma NK, Lakshminarayanan R*. Antifungal properties of lecithin- and terbinafine-loaded electrospun poly (ε-caprolactone) nanofibres. 2016. RSC Adv . *Corresponding authors.

Zhao Z, Lee RT, GV Pusapati, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. 2016. EMBO Reports.

Saheki Y, Bian X, Schauder CM, Sawaki Y, Surma MA, Klose C, Pincet F, Reinisch KM, De Camilli P. Control of plasma membrane lipid homeostasis by the extended synaptotagmins. 2016. Nature Cell Biology

Zhao Z, Lee RT, GV Pusapati, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. 2016. EMBO Reports.

Duong DT, Singh S, Bagheri M, Verma NK, Schmidtchen A, Malmsten M. Pronounced peptide selectivity for melanoma through tryptophan end-tagging. 2016. Sci Rep.

Bragge P, Synnot A, Maas AI, Menon DK, Cooper DJ, Rosenfeld JV, Gruen RL. A State-of-the-Science Overview of Randomized Controlled Trials Evaluating Acute Management of Moderate-to-Severe Traumatic Brain Injury. 2016. Journal of Neurotrauma

Kim HS, Cho HY, Augustine GJ, Han JH. Selective Control of Fear Expression by Optogenetic Manipulation of Infralimbic Cortex after Extinction. 2016. Neuropsychopharmacology

Mellado-Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Fuente-Martin E, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, de Gracia Herrera-Gómez I, López-Noriega L, Pérez-Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I, Gauthier BR. PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.2016. Diabetologia

Chng SH, Kundu P, Dominguez-Brauer C, Teo WL, Kawajiri K, Fujii-Kuriyama Y, Mak TW, Pettersson S. Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity. 2016. Scientific reports.

Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin R, Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Erratum: Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals. 2016. Scientific Report.

Duong DT, Singh S, Bagheri M, Verma NK, Schmidtchen A, Malmsten M. Pronounced peptide selectivity for melanoma through tryptophan end-tagging.2016. Scientific Reports

Yu H, Chakravorty S, Song W, Ferenczi MA. Phosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectives. 2016. Eur Biophys J.


May

Suter PM, Wahli W. "Every day I dream ..." An interview with the Rwandan Health Minister. 2016. Swiss Med Wkly.

van der Plas MJA, Bhongir RKV, Kjellström S, Siller H, Kasetty G, Mörgelin M, Schmidtchen A. Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses. 2016. Nature Communications

Rando G, Tan CK, Khaled N, Montagner A, Leuenberger N, Bertrand-Michel J, Paramalingam E, Guillou H, Wahli W. Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism. 2016. Elife

Dalan R, Liew H, Goh LL, Gao X, Chew DE, Boehm BO, Leow MK. The haptoglobin 2-2 genotype is associated with inflammation and carotid artery intima-media thickness. 2016. Diab Vasc Dis Res.

Curtis K, McCarthy A, Mitchell R, Black D, Foster K, Jan S, Burns B, Tall G, Rigby O, Gruen R, Kennedy B, Holland AJ. Paediatric trauma systems and their impact on the health outcomes of severely injured children: protocol for a mixed methods cohort study. 2016. Scand J Trauma Resusc Emerg Med.

Berglund K, Wen L, Dunbar RL, Feng G, Augustine GJ. Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers. 2016. J NeurosciGovindasamy G, Barber BE, Ghani SA, William T, Grigg MJ, Borooah S, Dhillon B, Dondorp AM, Yeo TW, Anstey NM, Maude RJ. Retinal Changes in Uncomplicated and Severe Plasmodium knowlesi Malaria. 2016. J Infect Dis

Buss L, Fisher E, Hardy J, Nizetic D, Groet J, Pulford L, Strydom A. Intracerebral haemorrhage in Down syndrome: protected or predisposed? 2016. F1000Res.

Datta A, Bhattacharyya D, Singh S, Ghosh A, Schmidtchen A, Malmsten M, Bhunia A.Role of Aromatic Amino Acids in Lipopolysaccharide and Membrane Interactions of Antimicrobial Peptides for Use in Plant Disease Control. 2016. The Journal of Biological Chemistry

Balasingam S, Wilder-Smith A. Randomized controlled trials for influenza drugs and vaccines: a review of controlled human infection studies.2016. International Journal of Infectious Diseases

Massad E, Tan SH, Khan K, Wilder-Smith A. Estimated Zika virus importations to Europe by travellers from Brazil.2016. Global Health Action Journal

Wilder-Smith A, Cohn E, Lloyd DC, Tozan Y, Brownstein JS. Internet-based media coverage on dengue in Sri Lanka between 2007 and 2015. 2016. Global Health Action Journal

Verma NK, Fazil MH, Ong ST, Chalasani ML, Low JH, Kottaiswamy A, P P, Kizhakeyil A, Kumar S, Panda AK, Freeley M, Smith SM, Boehm BO, Kelleher D. LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway.2016. Journal of Immunology

Villarreal R, Mitrofanova A, Maiguel D, Morales X, Jeon J, Grahammer F, Leibiger IB, Guzman J, Fachado A, Yoo TH, Busher Katin A, Gellermann J, Merscher S, Burke GW, Berggren PO, Oh J, Huber TB, Fornoni A. Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor. Journal of American Society of Nephrology

Govindasamy G, Barber BE, Ghani SA, William T, Grigg MJ, Borooah S, Dhillon B, Dondorp AM, Yeo TW, Anstey NM, Maude RJ. Retinal Changes in Uncomplicated and Severe Plasmodium knowlesi Malaria. 2016. J Infect Dis


June

Song SH, Augustine GJ. Synapsin Isoforms Regulating GABA Release from Hippocampal Interneurons. 2016. J Neurosci.
Toepfer C, West TG, Ferenczi MA. Revisiting Frank-Starling: regulatory light chain phosphorylation alters the rate of force redevelopment (ktr ) in a length-dependent fashion. 2016. J Physiol.
Grigg MJ, William T, Menon J, Barber BE, Wilkes CS, Rajahram GS, Edstein MD, Auburn S, Price RN, Yeo TW, Anstey NM. Efficacy of Artesunate-mefloquine for Chloroquine-resistant Plasmodium vivax Malaria in Malaysia: An Open-label, Randomized, Controlled Trial. 2016. Clin Infect Dis.
Lee HG, William T, Menon J, Ralph AP, Ooi EE, Hou Y, Sessions O, Yeo TW. Tuberculous meningitis is a major cause of mortality and morbidity in adults with central nervous system infections in Kota Kinabalu, Sabah, Malaysia: an observational study. 2016. BMC Infect Dis
Ang ML, Pethe K. Contribution of high-content imaging technologies to the development of anti-infective drugs. 2016. Cytometry A.
Padmanabhan P, Kumar A, Kumar S, Chaudhary RK, Gulyás B. Nanoparticles in practice for molecular-imaging applications: An overview.2016 Acta Biomaterialia
Billes V, Kovács T, Hotzi B, Manzéger A, Tagscherer K, Komlós M, Tarnóci A, Pádár Z, Erdős A, Bjelik A, Legradi A, Gulya K, Gulyás B, Vellai T. AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease.2016. Journal of Huntington’s Disease.
Eklund Y, Aronsson A, Schmidtchen A, Relander T. Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases. 2016. Acta Dermato-Venereologica
Rocklöv J, Quam MB, Sudre B, German M, Kraemer MU, Brady O, Bogoch II, Liu-Helmersson J, Wilder-Smith A, Semenza JC, Ong M, Aaslav KK, Khan K. Assessing Seasonal Risks for the Introduction and Mosquito-borne Spread of Zika Virus in Europe. 2016. EBioMedicine
Massad E, Tan SH, Khan K, Wilder-Smith A. Randomized controlled trials for influenza drugs and vaccines: a review of controlled human infection studies.2016. Global Health Action Journal.
Orsborne J, DeRaedt Banks S, Hendy A, Gezan SA, Kaur H, Wilder-Smith A, Lindsay SW, Logan JG. Personal Protection of Permethrin-Treated Clothing against Aedes aegypti, the Vector of Dengue and Zika Virus, in the Laboratory. 2016. PLOS ONE
van Velthoven MH, Mastellos N, Majeed A, O'Donoghue J, Car J. Feasibility of extracting data from electronic medical records for research: an international comparative study. 2016.BMC Medical Infromatics and Decision Making

July
Stifter K, Schuster C, Schlosser M, Boehm BO, Schirmbeck R. Exploring the induction of preproinsulin-specific Foxp3(+) CD4(+) Treg cells that inhibit CD8(+) T cell-mediated autoimmune diabetes by DNA vaccination. 2016. Scientific Report.
Hou HW, Petchakup C, Tay HM, Tam ZY, Dalan R, Chew DE, Li KH, Boehm BO. Rapid and label-free microfluidic neutrophil purification and phenotyping in diabetes mellitus. 2016. Scientific Report.
Verma NK, Fazil MH, Ong ST, Chalasani ML, Low JH, Kottaiswamy A, P P, Kizhakeyil A, Kumar S, Panda AK, Freeley M, Smith SM, Boehm BO. LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling-Dependent Notch Pathway. 2016. J Immunol.
Chin EW, Marcy G, Yoon SI, Ma D, Rosales FJ, Augustine GJ, Goh EL. Choline Ameliorates Disease Phenotypes in Human iPSC Models of Rett Syndrome. 2016. Neuromolecular Med.
Bird EM, Parameswaran U, William T, Khoo TM, Grigg MJ, Aziz A, Marfurt J, Yeo TW, Auburn S, Anstey NM, Barber BE. Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report. 2016. Malar J
Gilmartin DJ, Soon A, Thrasivoulou C, Phillips AR, Jayasinghe SN, Becker DL. Sustained Release of Cx43 Antisense Oligodeoxynucleotides from Coated Collagen Scaffolds Promotes Wound Healing. 2016. Adv Healthc Mater.
Zhang J, Jin X, Zhu Z, Huang L, Liang S, Xu Y, Liao R, Zhou L, Zhang Y, Wilder-Smith A. Early detection of Zika virus infection among travellers from areas of ongoing transmission in China. 2016.Journal of Travel Medicine
Massad E, Coutinho FA, Wilder-Smith A. Is Zika a substantial risk for visitors to the Rio de Janeiro Olympic Games? 2016. THE Lancet
Velumani S, Toh YX, Balasingam S, Archuleta S, Leo YS, Gan VC, Thein TL, Wilder-Smith A, Fink K.Low antibody titers 5 years after vaccination with the CYD-TDV dengue vaccine in both pre-immune and naïve vaccinees. 2016. Human Vaccines & Immunotherapeutics.
Greenfield R, Busink E, Wong CP, Riboli-Sasco E, Greenfield G, Majeed A, Car J, Wark PA. Truck drivers' perceptions on wearable devices and health promotion: a qualitative study. 2016. BMC Public Health.

Burattini MN, Coutinho FA, Lopez LF, Ximenes R, Quam M, Wilder-Smith A, Massad E. Potential exposure to Zika virus for foreign tourists during the 2016 Carnival and Olympic Games in Rio de Janeiro, Brazil. 2016. Epidemiol Infect.
Yong RY, Mustaffa SB, Wasan PS, Sheng L, Marshall CR, Scherer SW, Teo YY, Yap EP. Complex Copy Number Variation of AMY1 does not Associate with Obesity in two East Asian Cohorts. 2016. Hum Mutat.
August
Yang X, Murukeshan VM, Su HB, Padmanabhan P, Gulyás B. Nanoparticulate Contrast Agents for Multimodality Molecular Imaging. 2016. Journal of Biomedical Nanotechnology
Macinko J, Guanais FC, Mullachery P, Jimenez G. Gaps In Primary Care And Health System Performance In Six Latin American And Caribbean Countries. 2016. Health Affairs
Zarei M, Barroso E, Leiva R, Barniol-Xicota M, Pujol E, Escolano C, Vázquez S, Palomer X, Pardo V, González-Rodríguez Á, Valverde ÁM, Quesada-López T, Villarroya F, Wahli W, Vázquez-Carrera M. Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and is Activated by PPARβ/δ Deficiency. 2016. Diabetes.
Murima P, Zimmermann M, Chopra T, Pojer F, Fonti G, Peraro M D, Alonso S, Sauer U, Pethe K, McKinney JD. A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria. 2016. Nat Commun
Bragge P, Synnot A, Maas AI, Menon DK, Cooper DJ, Rosenfeld JV, Gruen RL.. A State-of-the-Science Overview of Randomized Controlled Trials Evaluating Acute Management of Moderate-to-Severe Traumatic Brain Injury. 2016. J Neurotrauma.
Soon AS, Chua JW, Becker DL. Connexins in endothelial barrier function - novel therapeutic targets countering vascular hyperpermeability. 2016. Thromb Haemost.
Barrett DW, David AL, Thrasivoulou C, Mata A, Becker DL, Engels AC, Deprest JA, Chowdhury TT. Connexin 43 is overexpressed in human fetal membrane defects after fetoscopic surgery. 2016. Prenat Diagn.
Toepfer CN, Sikkel MB, Caorsi V, Vydyanath A, Torre I, Copeland O, Lyon AR, Marston SB, Luther PK, Macleod KT, West TG, Ferenczi MA. A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation. 2016. Am J Physiol Heart Circ Physiol.
Jurek A, Genander M, Kundu P, Catchpole T, He X, Strååt K, Sabelström H, Xu NJ, Pettersson S, Henkemeyer M, Frisén J. Eph receptor interclass cooperation is required for the regulation of cell proliferation. 2016. Exp Cell Res.
Braun K, Pochert A, Lindén M, Davoudi M, Schmidtchen A, Nordström R, Malmsten M. Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides. 2016. J Colloid Interface Sci.
Amaku M, Azevedo F, Burattini MN, Coelho GE, Coutinho FA, Greenhalgh D, Lopez LF, Motitsuki RS, Wilder-Smith A, Massad E. Magnitude and frequency variations of vector-borne infection outbreaks using the Ross-Macdonald model: explaining and predicting outbreaks of dengue fever. 2016. Epidemiol Infect.
Wilder-Smith A, Vannice KS, Hombach J, Farrar J, Nolan T. Population perspectives and WHO recommendations for CYD-TDV dengue vaccine. 2016. J Infect Dis.
Massad E, Coutinho FA, Wilder-Smith A. The olympically mismeasured risk of Zika virus in Rio de Janeiro - Authors' reply. 2016. Lancet.
Samra R, Car J, Majeed A, Vincent C, Aylin P. How to monitor patient safety in primary care? Healthcare professionals' views. 2016. JRSM Open.

Synnot A, Gruen RL, Menon D, Steyerberg EW, Buki A, Peul WC, Elliott JH, Maas A. A New Approach to Evidence Synthesis in Traumatic Brain Injury: A Living Systematic Review. 2016. Journal of Neurotrauma


September

Chandy KG, Norton RS. Immunology: Channelling potassium to fight cancer. 2016. Nature

Tan NS, Vázquez-Carrera M, Montagner A, Sng MK, Guillou H, Wahli W. Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ. 2016. Prog Lipid Res.
Tay MY, Smith K, Ng IH, Chan KW, Zhao Y, Ooi EE, Lescar J, Luo D, Jans DA, Forwood JK, Vasudevan SG. The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. 2016. PLoS Pathogen
Tomas J, Mulet C, Saffarian A, Cavin JB, Ducroc R, Regnault B, Kun Tan C, Duszka K, Burcelin R, Wahli W, Sansonetti PJ, Pédron T. High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine. 2016. PNAS
Barbaric J, Abbott R, Posadzki P, Car M, Gunn LH, Layton AM, Majeed A, Car J. Light therapies for acne. 2016. Cochrane Database Syst Rev.
Ratanawong P, Kittayapong P, Olanratmanee P, Wilder-Smith A, Byass P, Tozan Y, Dambach P, Quiñonez CA, Louis VR. Spatial Variations in Dengue Transmission in Schools in Thailand. 2016. PLoS One.
Barber BE, William T, Grigg MJ, Piera KA, Chen Y, Wang H, Weinberg JB, Yeo TW, Anstey NM. Nitric oxide dependent endothelial dysfunction and reduced arginine bioavailability in vivax malaria but no greater increase in intravascular haemolysis in severe disease. 2016. J Infect Dis.
Barber BE, Grigg MJ, William T, Yeo TW, Anstey NM. Intravascular haemolysis with haemoglobinuria in a splenectomized patient with severe Plasmodium knowlesi malaria. 2016. Malar J.
Boyd JM, Burton R, Butler BL, Dyer D, Evans DC, Felteau M, Gruen RL, Jaffe KM, Kortbeek J, Lang E, Lougheed V, Moore L, Narciso M, Oxland P, Rivara FP, Roberts D, Sarakbi D, Vine K, Stelfox HT. Development and Validation of Quality Criteria for Providing Patient- and Family-centered Injury Care. 2016. Annals of Surgery.
Saleh K, Sonesson A, Persson K, Riesbeck K, Schmidtchen A. Can dressings soaked with polyhexanide reduce bacterial loads in full-thickness skin grafting? A randomized controlled trial. 2016. Journal of the American Academy of Dermatology.
Järbrink K, Ni G, Sönnergren H, Schmidtchen A, Pang C, Bajpai R, Car J. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. 2016. Syst Rev.
Fang SH, Suzuki K, Lim CL, Chung MS, Ku PW, Chen LJ. Associations between sleep quality and inflammatory markers in patients with schizophrenia. 2016. Psychiatry Res.
Tudor Car L, Papachristou N, Bull A, Majeed A, Gallagher J, El-Khatib M, Aylin P, Rudan I, Atun R, Car J, Vincent C. Clinician-identified problems and solutions for delayed diagnosis in primary care: a PRIORITIZE study. 2016. BMC Fam Pract.
Quam MB, Wilder-Smith A. Estimated global exportations of Zika virus infections via travellers from Brazil from 2014 to 2015. 2016. J Travel Med.
Koubassova NA, Bershitsky SY, Ferenczi MA, Narayanan T, Tsaturyan AK. Tropomyosin movement is described by a quantitative high-resolution model of X-ray diffraction of contracting muscle. 2016. Eur Biophys J

October
 
Barber BE, Grigg MJ, William T, Yeo TW, Anstey NM. The Treatment of Plasmodium knowlesi Malaria. 2016. Trends Parasitol.
 
Hector A, Chotirmall SH, Lavelle GM, Mirković B, Horan D, Eichler L, Mezger M, Singh A, Ralhan A, Berenbrinker S, Mack I, Ensenauer R, Riethmüller J, Graepler-Mainka U, Murray MA, Griese M, McElvaney NG, Hartl D. Chitinase activation in patients with fungus-associated cystic fibrosis lung disease. 2016. J Allergy Clin Immunol.
 
Rajesh D, Muthukumar S, Saibaba G, Siva D, Akbarsha MA, Gulyás B, Padmanabhan P, Archunan G. Structural elucidation of estrus urinary lipocalin protein (EULP) and evaluating binding affinity with pheromones using molecular docking and fluorescence study. 2016. Sci Rep
 
Dhand C, Ong ST, Dwivedi N, Diaz SM, Venugopal JR, Navaneethan B, Fazil MH, Liu S6, Seitz V, Wintermantel E, Beuerman RW, Ramakrishna S, Verma NK, Lakshminarayanan R. Bio-inspired in situ crosslinking and mineralization of electrospun collagen scaffolds for bone tissue engineering. 2016. Biomaterials.
 

November
 
 
Lee RT, Ng AS, Ingham PW. Ribozyme Mediated gRNA Generation for In Vitro and In Vivo CRISPR/Cas9 Mutagenesis. 2016. PLoS One
 
Kumar A, Narayanan K, Chaudhary RK, Mishra S, Kumar S, Vinoth KJ, Padmanabhan P, Gulyás B. Current Perspective of Stem Cell Therapy in Neurodegenerative and Metabolic Diseases. 2016. Mol Neurobiol
 
Dhand C, Barathi VA, Ong ST, Venkatesh M, Harini S, Dwivedi N, Goh ETL, Nandhakumar M, Venugopal JR, Diaz SM, Fazil MHUT, Loh XJ, Ping LS, Beuerman RW, Verma NK, Ramakrishna S, Lakshminarayanan R. Latent oxidative polymerization of catecholamines as potential cross-linkers for biocompatible and multifunctional biopolymer scaffolds. 2016. ACS Appl Maters Interfaces.
 
Makino H, Hwang E, Hedrick N and Komiyama T. Circuit mechanisms of sensorimotor learning. 2016. Neuron
 
Wilder-Smith A, Vannice KS, Hombach J, Farrar J, Nolan T. Population Perspectives and World Health Organisation Recommendations for CYD-TDV Dengue Vaccine. The Journal of Infectious Diseases, 2016
 
Duszka K, Picard A, Ellero-Simatos S, Chen J, Defernez M, Paramalingam E, Pigram A, Vanoaica L, Canlet C, Parini P, Narbad A, Guillou H, Thorens B, Wahli W. Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction. 2016. Scientific Reports
 
Fazil MHUT, Ong ST, Chalasani MLS, Low JH, Kizhakeyil A, Mamidi A, Lim CFH, Wright GD, Lakshminarayanan R, Kelleher D, Verma NK. GapmeR cellular internalization by macropinocytosis induces sequence-specific gene silencing in human primary T-cells. 2016. Scientific Reports.
 
Hamer DH, Barbre KA, Chen LH, Grobusch MP, Schlagenhauf P, Goorhuis A, van Genderen PJ, Molina I, Asgeirsson H, Kozarsky PE, Caumes E, Hagmann SH, Mockenhaupt FP, Eperon G, Barnett ED, Bottieau E, Boggild AK, Gautret P, Hynes NA, Kuhn S, Lash RR, Leder K, Libman M, Malvy DJ, Perret C, Rothe C, Schwartz E, Wilder-Smith A, Cetron MS, Esposito DH; GeoSentinel Surveillance Network. Travel-Associated Zika Virus Disease Acquired in the Americas Through February 2016: A GeoSentinel Analysis. 2016. Ann Intern Med.
 
Phoo WW, Li Y, Zhang Z, Lee MY, Loh YR, Tan YB, Ng EY, Lescar J, Kang C, Luo D. Structure of the NS2B-NS3 protease from Zika virus after self-cleavage. 2016. Nat Commun.
 
Paul DS, Teschendorff AE, Dang MA, Lowe R, Hawa MI, Ecker S, Beyan H, Cunningham S, Fouts AR, Ramelius A, Burden F, Farrow S, Rowlston S, Rehnstrom K, Frontini M, Downes K, Busche S, Cheung WA, Ge B, Simon MM, Bujold D, Kwan T, Bourque G, Datta A, Lowy E, Clarke L, Flicek P, Libertini E, Heath S, Gut M, Gut IG, Ouwehand WH, Pastinen T, Soranzo N, Hofer SE, Karges B, Meissner T, Boehm BO, Cilio C, Elding Larsson H, Lernmark Å, Steck AK, Rakyan VK, Beck S, Leslie RD. Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. 2016. Nat Commun.
 
Chua SL, Ding Y, Liu Y, Cai Z, Zhou J, Swarup S, Drautz-Moses DI, Schuster SC, Kjelleberg S, Givskov M, Yang L.. Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels. 2016. Open Biol.
 
Lee HU, McPherson ZE, Tan B, Korecka A, Pettersson S. Host-microbiome interactions: the aryl hydrocarbon receptor and the central nervous system. 2016. J Mol Med (Berl).
 
Chue S. Discourse analysis for understanding nature of facilitation and teaching approaches in interprofessional education. 2016. Med Teach.
 
Liyanage P, Tissera H, Sewe M, Quam M, Amarasinghe A, Palihawadana P, Wilder-Smith A, Louis VR, Tozan Y, Rocklöv J. A Spatial Hierarchical Analysis of the Temporal Influences of the El Niño-Southern Oscillation and Weather on Dengue in Kalutara District, Sri Lanka. 2016. Int J Environ Res Public Health.
 
Pan DS, Huang JH, Lee MH, Yu Y, Chen MI, Goh EH, Jiang L, Chong JW, Leo YS, Lee TH, Wong CS, Loh VW, Poh AZ, Tham TY, Wong WM, Lim FS. Knowledge, attitudes and practices towards antibiotic use in upper respiratory tract infections among patients seeking primary health care in Singapore. 2016. BMC Fam Pract.
 
Sun H, Yeo WL, Lim YH, Chew X, Smith DJ, Xue B, Chan KP, Robinson RC, Robins EG, Zhao H, Ang EL. Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate. 2016. Angew Chem Int Ed Engl.
 
Chua EG, Wise MJ, Khosravi Y, Seow SW, Amoyo AA, Pettersson S, Peters F, Tay CY, Perkins TT, Loke MF, Marshall BJ, Vadivelu J. Quantum changes in Helicobacter pylori gene expression accompany host-adaptation. 2016. DNA Res.
 
Chia AR, de Seymour JV, Colega M, Chen LW, Chan YH, Aris IM, Tint MT, Quah PL, Godfrey KM, Yap F, Saw SM, Baker PN, Chong YS, van Dam RM, Lee YS, Chong MF. A vegetable, fruit, and white rice dietary pattern during pregnancy is associated with a lower risk of preterm birth and larger birth size in a multiethnic Asian cohort: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study. 2016. Am J Clin Nutr.
 
Tudor Car L, Papachristou N, Gallagher J, Samra R, Wazny K, El-Khatib M, Bull A, Majeed A, Aylin P, Atun R, Rudan I, Car J, Bell H, Vincent C, Franklin BD. Identification of priorities for improvement of medication safety in primary care: a PRIORITIZE study. 2016. BMC Fam Pract.
 
Thiruppathi R. Mishra S, Ganapathy M, Padmanabhan P, Gulyás B. Nanoparticle Functionalization and Its Potentials for Molecular Imaging. 2016. Advanced Science
 
Gurung R, Ono Y, Baxendale S, Lee SL, Moore S, Calvert M, Ingham PW. The Zebrafish frozen Mutant Is a Model for Human Myopathy Associated with Mutation of the Unconventional Myosin MYO18B. 2016. Genetics
 

December

 
Ng DH, Wong JG, Thein TL, Leo YS, Lye DC. The Significance of Prolonged and Saddleback Fever in Hospitalised Adult Dengue. 2016. PLoS One
 
Liow SS, Dou Q, Kai D, Li Z, Sugiarto S, Yu CY, Kwok RT, Chen X, Wu YL, Ong ST, Kizhakeyil A, Verma NK, Tang BZ, Loh XJ. Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer. 2016. Small
 
Manickam R, Wahli W. Roles of peroxisome proliferator-activated receptor β/δ in skeletal muscle physiology. 2016. Biochimie.
 
Lim CL. Look beyond Thermoregulation and Hydration in the Diagnosis of Heat Stroke. 2016. Med Sci Sports Exerc.
 
Goh YY, Yan YK, Tan NS, Goh SA, Li S, Teoh YC, Lee PP. Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex. 2016. Sci Rep
 
Saibaba G, Rajesh D, Muthukumar S, Sathiyanarayanan G, Padmanabhan P, Akbarsha MA, Gulyás B, Archunan G. Proteomic analysis of human saliva: An approach to find the marker protein for ovulation. 2016. Reprod Biol.
 
Finkelstein EA, Haaland BA, Bilger M, Sahasranaman A, Sloan RA, Nang EE, Evenson KR. Effectiveness of activity trackers with and without incentives to increase physical activity (TRIPPA): a randomised controlled trial. 2016. Lancet Diabetes Endocrinol.
 
Bose T, Diedrichs-Möhring M, Wildner G. Dry eye disease and uveitis: A closer look at immune mechanisms in animal models of two ocular autoimmune diseases. 2016. Autoimmun Rev.
 
Chue S. Professional learning communities for enhancing faculty development initiatives. 2016. Med Teach
 
Pua U, Quek LH, Tan GW. Transvenous Salvage of Migrated Large Volume Detachable Coil. 2016. Cardiovasc Intervent Radiol.
 
Zhang Z, Yan Li Y, Loh YR, Phoo WW, Alvin W. Hung, Kang C, Luo D. Crystal structure of unlinked NS2B-NS3 protease from Zika virus. 2016. Science
 
Young B, Zhao X, Cook AR, Parry CM, Wilder-Smith A, I-Cheng MC. Do antibody responses to the influenza vaccine persist year-round in the elderly? A systematic review and meta-analysis. 2016. Vaccine.
 
Wilder-Smith A, Gubler DJ, Weaver SC, Monath TP, Heymann DL, Scott TW. Epidemic arboviral diseases: priorities for research and public health. 2016. The Lancet Infectious Disease.
 
Wilder-Smith A, Monath TP. Responding to the threat of urban yellow fever outbreaks. 2016. The Lancet Infectious Disease.
 
McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST; CAMP Research Group. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. 2016. Am J Respir Crit Care Med.
 
Augustine GJ, Fivaz M. Editorial: Imaging Synapse Structure and Function. 2016. Front Synaptic Neurosci.
 
Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK. Genome-wide association study of Parkinson's disease in East Asians. 2016. Hum Mol Genet.
 
Almaça J, Molina J, Menegaz D, Pronin AN, Tamayo A, Slepak V, Berggren PO, Caicedo A. Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells. 2016. Cell Rep.
 
Goh CC, Li JL, Becker D, Weninger W, Angeli V, Ng LG. Inducing Ischemia-reperfusion Injury in the Mouse Ear Skin for Intravital Multiphoton Imaging of Immune Responses. 2016. J Vis Exp.
 
Car LT, Papachristou N, Urch C, Majeed A, El-Khatib M, Aylin P, Atun R, Car J, Vincent C. Preventing delayed diagnosis of cancer: clinicians' views on main problems and solutions. J Glob Health. 2016
 
Posadzki P, Mastellos N, Ryan R, Gunn LH, Felix LM, Pappas Y, Gagnon MP, Julious SA, Xiang L, Oldenburg B, Car J. Automated telephone communication systems for preventive healthcare and management of long-term conditions. 2016. Cochrane Database Syst Rev.
 
EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz AJ, Akram A, Kondapally Seshasai SR, Cole D, Watts GF, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Freiberger T, Abifadel M, Aguilar-Salinas CA, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Ceska R, Corral P, Descamps O, Dieplinger H, Do CT, Durst R, Ezhov MV, Fras Z, Gaita D, Gaspar IM, Genest J, Harada-Shiba M, Jiang L, Kayikcioglu M, Lam CS, Latkovskis G, Laufs U, Liberopoulos E, Lin J, Lin N, Maher V, Majano N, Marais AD, März W, Mirrakhimov E, Miserez AR, Mitchenko O, Nawawi H, Nilsson L, Nordestgaard BG, Paragh G, Petrulioniene Z, Pojskic B, Reiner Ž, Sahebkar A, Santos LE, Schunkert H, Shehab A, Slimane MN, Stoll M, Su TC, Susekov A, Tilney M, Tomlinson B, Tselepis AD, Vohnout B, Widén E, Yamashita S, Catapano AL, Ray KK. Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration. 2016. Atheroscler Suppl.
 
Fialová S, Augustin M, Fischak C, Schmetterer L, Handschuh S, Glösmann M, Pircher M, Hitzenberger CK, Baumann B. Posterior rat eye during acute intraocular pressure elevation studied using polarization sensitive optical coherence tomography. 2016. Biomed Opt Express.