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Health for Life in Singapore Study (HELIOS)

​​The Health for Life in Singapore (HELIOS) Study is a state-of-the-art prospective cohort study, established and led by LKCMedicine, and involving both NHG and Imperial College London. We plan to identify the genetic and environmental factors that underpin development of obesity, diabetes, cardiovascular disease and other complex diseases in Singapore. Our ultimate goal is to use the knowledge generated to develop new approaches for prediction, prevention, early detection and better treatment of these chronic diseases.

We are studying 10,000 Singaporeans from the three main groups (Chinese, Malay, and Indian). At the baseline visit, we collect comprehensive, high quality phenotypic information from each participant, comprising health and lifestyle questionnaires, physical measurements, and extensive physiological and imaging data. In addition, biological samples are collected and a panel of biological markers is measured in the blood. Participants will then be followed up long-term to identify changes in health status, including new onset diseases.

The unique and extensive phenotypic measurements collected, together with biological samples and longterm follow-up, will enable investigation of the complex interrelationships between environmental, lifestyle and genetic factors on subsequent disease risk. The HELIOS study will provide a powerful resource for medical researchacross a wide range of disciplines that will be accessible to biomedical researchers worldwide.​
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