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Research Facilities

​​The LKCMedicine research laboratories are designed on an “open-lab” principle, with no walls or partitions separating one research group from another.

Open Lab Concept
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The open lab format facilitates communication between scientists with varying expertise to promote synergy in collaborative research and establishment of interdisciplinary research units. Bench space and support rooms are communal, as are the core facilities and common shared equipment such as biological safety cabinets, autoclaves, ultracentrifuges, incubators and other common sophisticated bench-top equipment like real-time PCRs and fluorescence plate readers.

Research Core Facility
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Our Research Core Facility covers imaging, flow cytometry, histology, a biological resource facility and other essential services to better support research at LKCMedicine. Where possible, new cutting-edge technologies or equipment are centrally acquired and shared.

Zebrafish Facility
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Zebrafish are a major model organism for biomedical research, due to relatively low costs, and ease of imaging and genetic manipulation. The Zebrafish Facility houses 2760 tanks and will provide researchers from Singapore with access to a range of wild-type, transgenic and mutant zebrafish lines. The facility also contains a quarantine room and can assist with the import and export of embryos, husbandry and IVF procedures, and has a nursery with robotic feeder for optimal growth rates. Procedure rooms are equipped with fluorescent microscopes for imaging as well as injection apparatus for generation of transgenics or knockouts.

Clinical Research Centre (CRC)
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The Clinical Research Centre (CRC) enables the conduct of clinical phase 1 trials of new medicines, which include Proof of Concept studies, Pharmacokinetic/Pharmacodynamic investigations, First-in-Human Trials and Interaction studies. These types of studies are complex and intensive and require experienced staff to manage them. Thus, the CRC is configured to provide infrastructural support for clinical studies and trials, including conducive facilities and consultation rooms, observation beds, a sample processing laboratory and biorepository. It can be used by LKCMedicine research staff, key clinical partners in the National Healthcare Group, collaborating institutions as well as the industry.
Rental

The research core facilities encompass a broad range of services, technology and expertise. The multidisciplinary scope of core facilities encourages sharing of scientific resources to enable focused development of technology that serves all research efforts across the spectrum of biomedical science. As a guiding principle, all faculty, their staff and students may utilise these shared resources.

Below is the list of approved charging rates for core facilities equipment and specialised equipment. The charging rates will be effective in January 2018.

For any enquiries, please contact Ken Wong @ kenwongkn@ntu.edu.sg

​​​Advanced Microscopy Facility ​Location ​​​User fee ($/hour)​ ​ ​
​​ ​​ Internal NTU Others
LSM800 Inverted Confocal with Airyscan​ EMB, Level 7 25 50 ​60​
LSM800 Upright Confocal-Zebrafish Facility EMB, Level 4  20 ​35 ​45​
Light sheet Microscope EMB, Level 4  30​ 60​ 75​
In Cell 2200 Analyser EMB, Level 7
20 45​ 60​
Slide Scanner CSB, Level 11 ​10 20​ 30​
Nikon TiE inverted fluorescence microscope EMB, 03-02Y ​8 15​ 20
Leica DM5500 upright Widefield EMB, 03-02Y
8 15 20
Leica SP8 upright Confocal  CSB, Level 12 ​25 50​ 60​
Leica SPE upright Confocal  CSB, Level 12 ​20 30​ 40​
Leica DMI6000 inverted Fluorescence Live Cell  CSB, Level 12 ​10 20​ 30
​​​Flow Cytometry Facility ​Location ​​​User Fee ($/Hour)​ ​ ​
​​ ​​ Internal NTU Others
BD LSRFortessa X-20 (5-lasers) EM​B, Level 7 15 40 60​​
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​​​Specialised Equipment ​Location ​​​User Fee ($/Hour)​ ​ ​
​​ ​​ Internal NTU ​Others
r EMB, Le vel 7 10 20 30
Glassware Washing Facility Location ​​​User Fee ($/Hour)​ ​ ​
​​ ​​ Internal NTU Others
Glassware washing service per basket E​MB, Level 2
CSB, Level 3
0 20 30

Core Research Platform @NTU - ​Histology Facility
Location​ ​​​User Fee ($/Hour)​ ​
​​ ​​ Internal NTU Others
Leica Automated Tissue Processor ASP6025 EMB, Level 7 10 20 30
Leica Crytostat CM3050S
EMB, Level 4 ​5 ​10 ​15
Leica Cicrotome RM2255
EMB, Level 7 ​5 ​10 ​​15
Leica Tissue Embedder EG1150 
​EMB, Level 7 ​5 ​10 ​15
Leica Autostainer XL
EMB, Level 7 ​10 0 ​​​30
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​*NOTE: LKCMedicine faculty and staff can refer to a more detailed specialised and general equipment list here
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